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However, currently, there is no evidence that products containing synthetic nicotine have different health effects or are less addictive than products containing tobacco-derived nicotine.37 E-cigarette brands advertise synthetic nicotine products online36 and marketing research38 projects a growth direction for the synthetic nicotine market from 2024 to 2030

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All methods performed in this study, including recruitment, informed consent, and human data collection, was carried out in accordance with the approved IRB protocol (No

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